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ASTHMA

DEXTRO CARDIA

 DEXTRO CARDIA:- 


• from Latin dexter, meaning "right," and Greek kardia, meaning "heart" 


DEFINITION:-  dextrocardia is a rare heart condition in which your heart points toward the right side of your chest instead of the left side 

• Dextrocardia is a congenital condition . 


 INCIDENCE :-

• Less than 1 % of the general population is born with dextrocardia.


TERMINOLOGY :-

• Dextroversion or Dextrorotation :-

• Rotation of heart around vertical axis  ,such that left ventricle lies anterior to right ventricle .

DEXTROPOSITION :-

• Anatomically normal heart is shifted to right due to someone acquired pathology ,such as right lung fibrosis ,collapse or left sided massive pleural effusion or pneumothorax etc. 



DEXTROCARDIA:-

• mirror image anatomical position along vertical axis. 

• Kartagener syndrome 

• Kartagener syndrome is when dextrocardia situs inversus is accompanied by primary ciliary dyskinesia, an inherited condition where the cilia that help move mucus become immobile. 

• Roughly 20 percent of those with dextrocardia also have Kartagener syndrome.


 TYPES:- 

There are two main types of dextrocardia: 

1. dextrocardia of embryonic arrest 

(also known as isolated dextrocardia) 

2. dextrocardia situs inversus. Dextrocardia situs inversus is further divided.


1. DEXTROCARDIA OF EMBRYONIC ARREST :-

• Also called as isolated dextrocardia ,

• the heart is simply placed further right in the thorax than is normal. 

• It is commonly associated with severe defects of the heart and related abnormalities including pulmonary hypoplasia. 


2.DEXTROCARDIA WITH SITUS INVERSUS :-

 Generally without any cardiac defect. 

the heart being a mirror image situated on the right side. For all visceral organs to be mirrored, the correct term is dextrocardia situs inversus totalis. 

Autosomal recessive condition. 

If situs  inversus is with levocardia, it is almost always associated with severe cardiac defects. 


• Overall incidence of dextrocardia : 1 in 12000 people .

ETIOLOGY :-

• Genetic predisposition 

(Autosomal recessive situs inversus ) 

• Problems during organogenesis and rotation of viscera. 

• Association with kartagener syndrome 

(50% of patients has situs inversus dextrocardia). 


ECG FEATURES:-

•  Right axis deviation 

• aVR  :-  upright P & T wave positive QRS. 

• Lead l :- inverted P , T &  Q R S 

• Chest leads :- absent  "r" progression 

Dominant  "s"  wave throughout.



SYMPTOMS:-

• Symptoms that require medical attention include: 

• unexplained and continual exhaustion 

• Inability to gain weight 

• Chronic infections, especially of the sinus and lungs 

• difficulty breathing 

• Jaundiced or yellowed skin 

• blue-tinted skin, especially around the fingers and toes


COMPLICATIONS 

• complications associated with dextrocardia may include: 

• When these anatomical differences occur, they can also make surgery difficult. 

• bowel disorders, usually from obstruction due to malrotation (reversal) 

• bronchial diseases, such as like chronic pneumonia, associated primarily with a loss of cilia (hair-like projections) from mucosal tissues 

• esophageal disorders 


• cardiovascular disorders 


• heart failure or disease 


• infection and sepsis


DIAGNOSIS 

• Most cases of dextrocardia are diagnosed using an electrocardiogram (EKG) and chest X-ray. 



• An EKG that shows inverted or reversed electrical waves usually points to dextrocardia. 

• Once a doctor suspects dextrocardia, they may use a computed tomography (CT) scan or a magnetic resonance imaging (MRI) scan to confirm the condition.


TREATMENT 

• A complete mirror image dextrocardia with no heart defects requires no treatment 

• The type of treatment needed depends on the heart or physical problems the infant may have in addition to dextrocardia. 

• If heart defects are present with dextrocardia ,the baby will most likely needed surgery. 


• MEDICATIONS :-

• Water piles (diuretics)

• Drugs that help the heart muscle pump more forcefully ( inotropic agents)

• Drugs that lower blood pressure and ease the workload on the heart (ACE inhibitors)




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